Smoking secession

24 studies

## $eff.studies
##          [,1]     [,2]     [,3]     [,4]
## [1,]       NA 1.525000 8.714286 2.904762
## [2,] 1.525000       NA 1.742857 1.742857
## [3,] 8.714286 1.742857       NA 3.388889
## [4,] 2.904762 1.742857 3.388889       NA
## 
## $eff.sz
##           [,1]     [,2]      [,3]     [,4]
## [1,]        NA 336.6626 4860.0123 834.1226
## [2,]  336.6626       NA  352.0526 383.2769
## [3,] 4860.0123 352.0526        NA 893.7265
## [4,]  834.1226 383.2769  893.7265       NA
## 
## $eff.prec
##            [,1]      [,2]      [,3]     [,4]
## [1,]         NA  9.531334 110.86594 19.21518
## [2,]   9.531334        NA  10.18933 11.00847
## [3,] 110.865935 10.189325        NA 21.31881
## [4,]  19.215176 11.008474  21.31881       NA

##       Modification Power AB Power AC Power AD
## 1         Original    0.188    0.934    0.621
## 2 Add one AB study    0.232    0.926    0.649
## 3 Add one AC study    0.213    0.921    0.654
## 4 Add one AD study    0.225    0.930    0.717

Diabetes

22 studies

## $studies
##      [,1] [,2] [,3] [,4] [,5] [,6]
## [1,]    0    3    2    2    2    1
## [2,]    3    0    1    1    3    2
## [3,]    2    1    0    5    3    1
## [4,]    2    1    5    0    3    1
## [5,]    2    3    3    3    0    0
## [6,]    1    2    1    1    0    0
## 
## $sz
##       [,1]  [,2]  [,3]  [,4]  [,5]  [,6]
## [1,]     0  7343  8752 15739 16488   392
## [2,]  7343     0  3315  9711 17893  9778
## [3,]  8752  3315     0 44974 15158  7999
## [4,] 15739  9711 44974     0 12597 10161
## [5,] 16488 17893 15158 12597     0     0
## [6,]   392  9778  7999 10161     0     0
## 
## $prec
##             [,1]      [,2]      [,3]      [,4]     [,5]        [,6]
## [1,]   0.0000000  88.57260  58.24722 169.84441 159.4093   0.8807101
## [2,]  88.5725968   0.00000  17.29006  79.55654 414.2068 133.1968547
## [3,]  58.2472157  17.29006   0.00000 758.55565 235.2112 128.2837360
## [4,] 169.8444148  79.55654 758.55565   0.00000 125.7409 322.9350792
## [5,] 159.4092870 414.20679 235.21118 125.74095   0.0000   0.0000000
## [6,]   0.8807101 133.19685 128.28374 322.93508   0.0000   0.0000000
## $eff.studies
##          [,1]     [,2]     [,3]     [,4]     [,5]     [,6]
## [1,]       NA 6.399267 6.197621 6.197621 6.151408 3.724947
## [2,] 6.399267       NA 5.619489 5.619489 6.352727 4.100939
## [3,] 6.197621 5.619489       NA 8.500000 7.047698 3.725881
## [4,] 6.197621 5.619489 8.500000       NA 7.047698 3.725881
## [5,] 6.151408 6.352727 7.047698 7.047698       NA 3.405458
## [6,] 3.724947 4.100939 3.725881 3.725881 3.405458       NA
## 
## $eff.sz
##          [,1]     [,2]     [,3]     [,4]     [,5]     [,6]
## [1,]       NA 26975.65 33068.58 36917.09 35049.50 17424.09
## [2,] 26975.65       NA 29904.63 33362.88 34413.48 21254.72
## [3,] 33068.58 29904.63       NA 65078.14 38825.21 22823.45
## [4,] 36917.09 33362.88 65078.14       NA 40724.69 24153.45
## [5,] 35049.50 34413.48 38825.21 40724.69       NA 18922.58
## [6,] 17424.09 21254.72 22823.45 24153.45 18922.58       NA
## 
## $eff.prec
##          [,1]     [,2]      [,3]      [,4]     [,5]     [,6]
## [1,]       NA 319.8832  345.1657  381.1067 375.3234 252.3803
## [2,] 319.8832       NA  397.4992  430.7574 596.8802 332.7694
## [3,] 345.1657 397.4992        NA 1014.1278 515.8685 436.8640
## [4,] 381.1067 430.7574 1014.1278        NA 520.4834 521.7865
## [5,] 375.3234 596.8802  515.8685  520.4834       NA 329.1284
## [6,] 252.3803 332.7694  436.8640  521.7865 329.1284       NA

## Random-effects model used (moderate heterogeneity assumed).

## Power: 40.76%
##    event1   n1 event2   n2 event3  n3 treat1 treat2 treat3
## 1       9  140     23  140     10 138      A      C      D
## 2      11   78     12   85     29 170      B      C      D
## 3      75  731    363  714     NA  NA      A      C       
## 4       2  106      9  205     NA  NA      A      C       
## 5      58  549    237 1561     NA  NA      A      C       
## 6       0   33      9   48     NA  NA      A      C       
## 7       3  100     31   98     NA  NA      A      C       
## 8       1   31     26   95     NA  NA      A      C       
## 9       6   39     17   77     NA  NA      A      C       
## 10     79  702     77  694     NA  NA      A      B       
## 11     18  671     21  535     NA  NA      A      B       
## 12     64  642    107  761     NA  NA      A      C       
## 13      5   62      8   90     NA  NA      A      C       
## 14     20  234     34  237     NA  NA      A      C       
## 15      0   20      9   20     NA  NA      A      D       
## 16      8  116     19  149     NA  NA      A      B       
## 17     95 1107    143 1031     NA  NA      A      C       
## 18     15  187     36  504     NA  NA      A      C       
## 19     78  584     73  675     NA  NA      A      C       
## 20     69 1177     54  888     NA  NA      A      C       
## 21     20   49     16   43     NA  NA      B      C       
## 22      7   66     32  127     NA  NA      B      D       
## 23     12   76     20   74     NA  NA      C      D       
## 24      9   55      3   26     NA  NA      C      D
##    study treatment sampleSize responders
## 1      1         A        140          9
## 2      1         C        140         23
## 3      1         D        138         10
## 4      2         B         78         11
## 5      2         C         85         12
## 6      2         D        170         29
## 7      3         A        731         75
## 8      3         C        714        363
## 9      4         A        106          2
## 10     4         C        205          9
## 11     5         A        549         58
## 12     5         C       1561        237
## 13     6         A         33          0
## 14     6         C         48          9
## 15     7         A        100          3
## 16     7         C         98         31
## 17     8         A         31          1
## 18     8         C         95         26
## 19     9         A         39          6
## 20     9         C         77         17
## 21    10         A        702         79
## 22    10         B        694         77
## 23    11         A        671         18
## 24    11         B        535         21
## 25    12         A        642         64
## 26    12         C        761        107
## 27    13         A         62          5
## 28    13         C         90          8
## 29    14         A        234         20
## 30    14         C        237         34
## 31    15         A         20          0
## 32    15         D         20          9
## 33    16         A        116          8
## 34    16         B        149         19
## 35    17         A       1107         95
## 36    17         C       1031        143
## 37    18         A        187         15
## 38    18         C        504         36
## 39    19         A        584         78
## 40    19         C        675         73
## 41    20         A       1177         69
## 42    20         C        888         54
## 43    21         B         49         20
## 44    21         C         43         16
## 45    22         B         66          7
## 46    22         D        127         32
## 47    23         C         76         12
## 48    23         D         74         20
## 49    24         C         55          9
## 50    24         D         26          3
treat1 treat2 treat3 event1 n1 event2 n2 event3 n3
A C D 9 140 23 140 10 138
B C D 11 78 12 85 29 170
A C 75 731 363 714
A C 2 106 9 205
A C 58 549 237 1561
A C 0 33 9 48
A C 3 100 31 98
A C 1 31 26 95
A C 6 39 17 77
A B 79 702 77 694
A B 18 671 21 535
A C 64 642 107 761
A C 5 62 8 90
A C 20 234 34 237
A D 0 20 9 20
A B 8 116 19 149
A C 95 1107 143 1031
A C 15 187 36 504
A C 78 584 73 675
A C 69 1177 54 888
B C 20 49 16 43
B D 7 66 32 127
C D 12 76 20 74
C D 9 55 3 26
study treatment sampleSize responders
1 A 140 9
1 C 140 23
1 D 138 10
2 B 78 11
2 C 85 12
2 D 170 29
3 A 731 75
3 C 714 363
4 A 106 2
4 C 205 9
5 A 549 58
5 C 1561 237
6 A 33 0
6 C 48 9
7 A 100 3
7 C 98 31
8 A 31 1
8 C 95 26
9 A 39 6
9 C 77 17
10 A 702 79
10 B 694 77
11 A 671 18
11 B 535 21
12 A 642 64
12 C 761 107
13 A 62 5
13 C 90 8
14 A 234 20
14 C 237 34
15 A 20 0
15 D 20 9
16 A 116 8
16 B 149 19
17 A 1107 95
17 C 1031 143
18 A 187 15
18 C 504 36
19 A 584 78
19 C 675 73
20 A 1177 69
20 C 888 54
21 B 49 20
21 C 43 16
22 B 66 7
22 D 127 32
23 C 76 12
23 D 74 20
24 C 55 9
24 D 26 3